Tuesday, 9 February 2016

Plavix: Promising Approach to Stop Blood Clot Formation

Plavix is an exceptional anti-platelet drug to prevent platelets in your blood from fixing together, resulting in blood clot formation that would check blood flow. The formation of blood clots occurs when certain blood cells, named platelets, make a cluster together. Generic Clopidogrel Bisulfate is present in this medication as active drug. Unnecessary blood clot formation can take place with certain heart or blood vessel conditions. Plavix is indicated to inhibit the formation of blood clots following a recent heart problem like stroke or heart attack. It can be also given to individuals who have peripheral artery disease or unstable angina (chest pain), and poor circulation in their legs. This medicine aids in easy flow of blood, in this way lowers the possibilities of a future heart attack or stroke.

The cardiovascular system encompasses the heart, blood and blood vessels. Blood contains several components including: white blood cells which fight infection; red blood cells which transfer oxygen; and platelets help in blood clot formation. And you also know that fatty substances like cholesterol also flow in the blood. The plaque or deposited cholesterol can accumulate over time, leading to narrowing and hardening of smooth artery walls.
Heart is a pump, and similar to other pumps, it can also become blocked, break down and need repair. 

When plaque deposits in a blood vessel, it gets damaged, platelets repair it through a 3-staged procedure called blood clotting. Firstly, the platelets get attached to the injured vessel wall. Secondly, certain chemicals called ADP are released from the platelets. ADP gets attached to the receptors present on platelets, modifying other receptors to draw the molecule, fibrinogen. Fibrinogen makes up fibrin which makes connections between platelets. This configuration traps RBCs and other platelets to form a clot. Some risk factors involved in the formation of blood clot include: obesity, smoking, coronary artery disease, surgical recovery and genetic factors.
In such cases, anti-platelet medicines can be of great help by preventing unwanted clots from forming. And Plavix is one such unique anti-platelet medication which offers great help.


Plavix belongs to oral, thienopyridine category of antiplatelet medicines. This medication inhibits the build-up of platelets, as a result blocks the formation of thrombus (clot). Clopidogrel is successful in the circulation of the arteries, where blood thinners are not.
Plavix is usually taken one time in a day. It's an excellent idea to take this medication with food so as to decrease the side effects. Most individuals with heart attack or unstable angina start with a 300mg dose, after that 75mg once per day, consumed in combination with 75 to 325mg of Aspirin. If you have had a recent stroke or suffer from peripheral arterial disease, your physician will possibly recommend a dose of 75mg Plavix daily.
Side effects associated with the use of this medicine may include rashes, diarrhea, serious neutropenia (reduction in WBCs), sudden numbness or weakness, Purpura (purple staining of the skin), Pruritus (restricted or generalized itching). If you get any of these side effects or they trouble you, contact your doctor right away before these persist.
PRECAUTIONS!!
  • Do not take Plavix if you have a head injury that leads to blood loss in the brain or a stomach ulcer.
  • Limit the intake of alcohol along with this drug as it can increase the risk of intestinal or stomach bleeding.
  • Plavix should be used with care in people suffering from hepatic and renal impairment.
  • Avoid this medication in case you have a history of stomach ulcer, stroke, including mini-stroke, and ulcerative colitis.
  • While taking Plavix, it is significant to keep away from activities that trigger injury or bleeding. You must also be vigilant about eliciting bleeding when you brush your teeth or shave.

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